How many different kinds of antihistamines is it safe to take at one time?
Asking for a friend.
I've taken two before.
I didn't notice any ill effects.
I once had a prescribed antihistamine, hydroxyzine? for anxiety... the same doctor gave me an rx for benzos...
They did not mix well at all...either that or I had a stroke... I couldn't speak for half an hour upon waking the next morning and for the rest of the morning it was still difficult to speak, some words just wouldn't form for some reason. The doctor prescribed the antihistamine because I asked for it... because the melting "quick relief" benzo she had given me wasn't working and I wanted to have something else I could take that wouldn't interact with it in case it all of a sudden did start to work.
Anyway, yeah, dr gave me benzo + antihistamine that was supposed to be fine, wasn't fine.
But that same antihistamine with dramamine was fine. Pretty sure but not 100% sure that I also took it with benadryl at least once.
Also I only ever take low/normal doses of anything so my experiences would be with low/normal dose ranges.