I do. I use it on my knees sometimes, especially after extra-long runs or bike rides. I don't use it topically every day, but I do use CBD oil tincture, vape, and edibles every day for anxiety and depression. I'm a mess without it. I got some lotion for my aunt about a month ago for her arthritis in her hands and she tells everyone how much her pain has decreased. I've taken it for years. One of my senior dogs takes it daily for his hips and one of my other dogs that passed last year used to take it for her anxiety. I can't say enough good about it (as long as it's from a reputable place). There's a lot of shit out there, too.