I almost didn't say anything, but FO76 kind of bothers me only because it takes a franchise I've played a lot in a direction that's popular for the moment (largely because it's cheaper to make) and I have zero interest in. PVP bores the crap out of me, I'm big into lots of story and NPCs, and one of my least favorite things about Fallout is the "you come upon a scene where someone needs a rescue but you're too late, they're dead" meme, which is repeated hundreds of times in Fallout 4, and apparently is almost every subplot in FO76.
Also, I have like 240 mods in FO4 because the vanilla game is kind of crap, and that's kind of like Skyrim or FO3. I live for mods.
Also, one of the 73 things I dislike about MMOs is meeting someone on a quest who is named ButtWrangle